The RNG will return the same sequence of random numbers, but doing things in a different order will have those numbers used for different purposes. So saving and trying the exact same shot again will give the same result. If you rolled a 23 and you needed >25 to hit, it will always miss no matter how many times you reload it because 23 will always be the first number in the sequence. But if you do some other action, that 23 gets used for that, and if 56 is the next number in the sequence then that shot will hit when you do it on the next action.
The RNG will return the same sequence of random numbers, but doing things in a different order will have those numbers used for different purposes. So saving and trying the exact same shot again will give the same result. If you rolled a 23 and you needed >25 to hit, it will always miss no matter how many times you reload it because 23 will always be the first number in the sequence. But if you do some other action, that 23 gets used for that, and if 56 is the next number in the sequence then that shot will hit when you do it on the next action.