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Cake day: June 23rd, 2023

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  • They make quality stuff for the prices, an old job got a bioreactor (basically a carboy for homebrewing wired with sensors & computer-controlled pumps) for $25k from a Chinese manufacturer. They later sold it to the Open Insulin project & used the money to buy a textured vegetable protein extruder from China to make vegan deli meats. Both had kinda wonky unintuitive user interfaces, but they were solid pieces of hardware











  • Not to mention meeting standards of purity and formulating your medication so it’s shelf stable and the active pharm ingredient can be distributed within the body effectively once the medicine is administered.

    I’ve had similar thoughts as these jokers but with using bioreactors. Each time I conclude that the solution is a centralized manufacturing facility owned by workers to effectively produce at scale (and ensure you don’t poison people).

    Sure, you’re not gonna build that misoprostol plant in Texas, but there’s other options to obtain properly-manufactured medication before you drink a mystery brew cooked up by an anarchist squatter named Spoon.


  • Absolutely, and I don’t see biohackers offering up cheap NMR or MS/MS detectors to solve the common issue of inadvertently making side products like MPTP when attempting to cook up MPPP or whatever, consequently injecting Parkinson’s into yourself. So you’re still bound by the enormous costs of getting an analytical lab stood up, despite using “AI” assisted synthetic software to substitute for real verification of each purified intermediate product. Also my other chem friend & I think that Vinni guy is an annoying ted-talk dude fwiw.


  • Very cool that they’ve published a FOSS version of in-silico synthetic software plus designed a jacketed reactor (much more convenient than babysitting a round bottomed flask in a mantle for 12 hours), but I can’t see it getting to very high or even mildy low temps.

    I don’t see much about cleaning the reactor feedlines or reactant reservoirs, nor how you take a reaction product and work it up, or purify it for that matter, in preparation for the next synthetic step. Classico synthesis traditionally structurally elucidates each step’s purified product with NMR before carrying it forward to the next rxn. But I’m a lazy chemist so I’d prefer to program microbes to make things for me (:







  • Shit sucks, I can commiserate. Last long term relationship I had was with a Tesla engineer that was a Hillary voter & The West Wing fan. Recently I almost considered moving across the country (to Bushwick lmao) for a Bernie volunteer that I began dating shortly before Oct 7 who turned out to be a radlib-y zionist with a temper. That person works as an economist for water, health, & sanitation NGOs and no longer considers themselves on the left.

    Our arguments got more and more frequent, with them going so far as to say the Nazis were actually socialist and that a secular 1 state solution would result in Palestinians outbreeding Jewish israelis & upset “israeli democracy”. She doesn’t want to talk since I dumped her for the above reasons, which tbf, did happen shortly after her dad died, but she was trying to force the issue of me moving in with her just 8 months into the relationship and I didn’t have a job lined up.