Aspartame is also linked in some studies to weight gain, GI disorders, mental health issues and more:

According to some studies, aspartame and other artificial sweeteners can lead to weight gain instead of weight loss 12. Aspartame has been linked to increased appetite, diabetes, metabolic derangement and obesity-related diseases 2.

One study showed that aspartame causes greater weight gain than a diet with the same calorie intake but no aspartame 1. Another study found that even acceptable daily intakes of aspartame might make you hungrier and lead to weight gain 3.

…some research suggests an association between aspartame intake and metabolic damage to the central nervous system (CNS), such as changes in enzyme and neurotransmitter activities 2. Aspartame acts as a chemical stressor by elevating plasma cortisol levels and causing the production of excess free radicals. High cortisol levels and excess free radicals may increase the brain’s vulnerability to oxidative stress which may have adverse effects on neurobehavioral health 3.

There is also some evidence that high-aspartame consumption may lead to weaker spatial orientation, irritability, depression, and other neurobehavioral conditions 14. However, these studies are limited in scope and further research is needed to determine the long-term effects of aspartame on human health.

Worth researching more, especially if you eat/drink anything with this stuff - and it’s in a lot of food products.

  • Zpiritual@lemmy.world
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    1 year ago

    Worth point out is that it doesn’t even reach the same classification as red meat which is classified as probably causing cancer.

    • sock@lemmy.world
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      1 year ago

      theres a lot of things that MIGHT cause cancer i feel like if youre drinking enough diet coke to cause cancer its not the sweetener its your impulse control

  • Don Corleone@lemmy.world
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    1 year ago

    Don’t freak out (yet) people…

    They put aspartame in the “possibly carcinogenic” category which is their least certain one. Also in this category we have… Radio waves (sigh)… Yeah right…

    • Richard@lemmy.world
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      1 year ago

      That’s always the problem with research, or rather with insufficient consumer protection laws. It needs time to run studies and provide reliable and definitive scientific results in an academic setting, and in the meantime, millions of human beings are exposed to toxic compounds. But because research cannot really be accelerated that much without a loss in quality, we should really push for better regulation of “experimental” products.

        • Richard@lemmy.world
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          1 year ago

          Yeah the EU supposedly regulates a lot more, but I cannot really feel much of that. In the end, we Europeans (I’m from Germany) have likely been exposed to as much aspartame as you have (assuming that you are American)

  • Required@lemmy.world
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    1 year ago

    Honestly nothing can be more dangerous than the OG coke. The amount of sugar in that can is incomprehensible

    • JesusTheCarpenter@lemmy.world
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      1 year ago

      This is another point that no-one makes. While it is clear that the best alternative to a sweetened drink would be water, often it is the “healthier and natural” version with real sugar which is just incomparably more damaging to human bodies.

  • Pietrasagh@lemmy.world
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    1 year ago

    Barbecue sausages are also carcinogenic. What matters is how much and in what doses. Hey WHO: Show me scientific, peer revieved, reproduced in independed labs papers with solid proofs. Not preliminary results of “one research”. Then I will weigh pros and cons and decide if I should use it. Strangely decades of use under supervision of FDA and other reputable institutions had no remarks like WHO. Don’t forget that dihydrate monoxide also promote cancer, and we all drink it like water.

    /edit typo, grammar/

  • varzaman@lemmy.one
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    1 year ago

    It’s not this straight forward. I read the reuters article about this that goes into more detail.

    https://www.reuters.com/business/healthcare-pharmaceuticals/whos-cancer-research-agency-say-aspartame-sweetener-possible-carcinogen-sources-2023-06-29/

    But basically, IARC is only looking at if the substance can be carcinogenic, regardless of the quantity it takes for it to be harmful to humans.

    There is another organization, called JECFA that is specifically for advice for individuals. This is where “food regulations” would come from.

    The JECFA is set to show off their findings at the same time as IARC is gonna make their announcement. I feel like some of you guys are jumping the gun here due to the title of the articles coming out.

  • ilex@lemmy.world
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    1 year ago

    Does aspartame cause cancer?

    In general, the American Cancer Society does not determine if something causes cancer (that is, if it is a carcinogen), but we do look to other respected organizations for help with this. Based on current research, some of these organizations have made the following determinations:

    The US Food and Drug Administration (FDA) has concluded that “the use of aspartame as a general purpose sweetener… is safe.”

    The European Food Safety Authority (EFSA) has stated, “Studies do not suggest an increased risk associated with aspartame consumption for… leukaemia, brain tumours or a variety of cancers, including brain, lymphatic and haematopoietic (blood) cancers.”

    Though research into a possible link between aspartame and cancer continues, these agencies agree that studies done so far have not found such a link.

    • coz@lemmy.world
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      1 year ago

      There was a study that found that Aspartame increased cancer risk, which was used as the base for all the current claims. The study was found to be flawed and it has not been reproduced since then, but due to confirmation bias and the desire to manipulate others the idea keeps communicating. That’s one weakness of science, you can make up research and the average person will use it to confirm their biases, even if it’s one study versus a hundred

      That being said, there may be other risks with artificial sweeteners, I’m just talking about that specific study

      Science is complicated and most people don’t know how to apply it. For example, an university graduate does not know how to read published research and how to apply it to the real world, because beyond training that needs a lot of practice and feedback. People think that hearing the news or reading the paper will let them know the truth; it won’t because they haven’t developed the capacity to do so, yet they ask for a source they can’t really understand. That’s why you are supposed to go to a professional instead of doing what you think you should do on your own

      The only people I’ve found that are worth giving sources to are PhDs or experts in their fields. Everyone else just fucks up interpreting them

  • JesusTheCarpenter@lemmy.world
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    1 year ago

    I am curious whether this will actually impact what is considered safe to consume on a daily basis.

    Again, many things are unhealthy and carcinogenic in large quantities. The infamos study showed that Aspartame was causing cancer in mice but the amounts they were given would be like humans eating bags of it every day.

  • gila@lemmy.world
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    1 year ago

    Obesity is like the second biggest risk factor for cancers. This post reads like a non-medical professional’s interpretation of medical advice. I don’t mean to offend, because that is very common. But the information presented here is devoid of context in a way that makes it potentially misleading.