3,3′-Diindolylmethane (DIM) decreased the Streptococcus mutans biofilm, a leading contributor to plaque and cavities, by 90%. A significant portion of the global population experiences persistent issues with dental plaque and cavities or will face them at some time. While toothpaste, mouthwash, and
DIM doesn’t increase estrogen, it reduces it. It forces the body to metabolize estradiol into 2-hydroxyestrone, which cannot be converted back to estradiol and has lower binding affinity, so it just gets pissed out. It’s often used for breast and thyroid cancer treatments.
So yeah, this could be really bad for women.