3,3′-Diindolylmethane (DIM) decreased the Streptococcus mutans biofilm, a leading contributor to plaque and cavities, by 90%. A significant portion of the global population experiences persistent issues with dental plaque and cavities or will face them at some time. While toothpaste, mouthwash, and
I read an article about that. IIRC it’s mainly because there is only minimal bloodflow in your teeth - barely enough to supply it with nutrients (and still not enough you should skip external flouride etc.).